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KMID : 1101020190440040183
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Journal of Oral Medicine and Pain
2019 Volume.44 No. 4 p.183 ~ p.188
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Treatment of Drug-Induced Erythema Multiforme: Case Report
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Lee Hae-Ohk
Ju Hye-Min
Lee Ji-Yeon
Jeon Hye-Mi
Kim Kyung-Hee
Ok Soo-Min
Ahn Yong-Woo
Jeong Sung-Hee
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Abstract
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Erythema multiforme (EM) is an inflammatory immune-mediated mucosal disease. EM is classified as EM minor or EM major, depending on the severity of symptoms. Most patients with minor or major forms of EM have oral lesions. EM can occur as a result of adverse drug reactions but this is difficult to establish. Several indicators have been developed that can be used as a criterion of evaluation to ensure objectivity in identifying the causality of adverse drug reactions. The Naranjo algorithm was used in the evaluation to ensure objectivity in identifying the causality of adverse drug reactions. There were two cases of patients suspected of having EM induced by drugs. They were both assessed using the Naranjo algorithm to confirm the causality of the disease.
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KEYWORD
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Drug-related side effects and adverse reactions, Erythema multiforme, Rheumatoid arthritis
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